What is Modafinil?
- Modafinil reduces excessive sleepiness, including conditions such as excessive daytime sleepiness.
- It is a prescription medication for people who struggle to stay awake due to narcolepsy (Ann Neurol. 1998), those working night shifts, or individuals with a changing shift pattern.
- Modafinil is also prescribed for some people with obstructive sleep apnoea.
- Research has examined Modafinil’s effect on cognitive function (Battleday & Brem, 2015) exploring its potential as a cognitive enhancer.
- It is usually prescribed for short-term use, as prolonged use may lead to dependence.
- Modafinil is a prescription drug often known by its brand name Provigil.
- Always read the patient information leaflet for a complete list of possible side effects, interactions, and precautions.
- Some people misuse Modafinil as a ‘smart drug’ or smart pill. Oxford University has reviewed its off-licence use (Oxford University) but it is not recommended by the MHRA due to the potential side effects.
Video: An overview of Modafinil
Watch the video below for a simple guide to Modafinil, including its uses, dosage, side effects and precautions.
How Does Modafinil Work?
Modafinil affects chemicals in the brain that control wakefulness, helping people feel more alert.
The body can develop a tolerance to Modafinil, which may lead to dependence if taken long-term. Stopping the medication suddenly can cause withdrawal symptoms. This is why Modafinil should only be used as prescribed, with regular reviews by a doctor to ensure it is still appropriate.

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