What is Dihydrocodeine?
Dihydrocodeine UK
- Dihydrocodeine is an opiate painkiller and a Class B controlled drug in the UK (BNF, 2023). It is regulated under the Misuse of Drugs Act 1971 and the Misuse of Drugs Regulations 2001 (GOV.UK, 2022).
- Some medications combine dihydrocodeine with paracetamol, such as co-dydramol.
- It is used to manage moderate to severe pain, including migraines, headaches, joint pain, muscle pain, toothache, and period pain (NHS, 2023).
- Available in both short-acting and sustained-release forms.
- Known under brand names such as DHC Continus and DF118 Forte.
- Dihydrocodeine tablets are a morphine derivative with moderate potency (Flecknell, P.; 2016)
- Always read the patient information leaflet for a complete list of side effects and precautions.
How Does Dihydrocodeine Work?
Dihydrocodeine is a semi-synthetic opioid that relieves pain by blocking pain signals in the central nervous system. It binds to opioid receptors, reducing or eliminating pain perception (Buckle, J., 2015). This means that your sensation of the pain is either reduced or eliminated (NHS, 2022).
It does not treat the underlying cause of pain but helps provide relief while recovering from an injury or surgery. Managing pain effectively can aid recovery, reducing the risk of post-operative complications such as blood clots or chest infections.
How is Dihydrocodeine taken?
Dihydrocodeine Tablets
Dihydrocodeine is available as tablets or liquid. Tablets should be swallowed with water.
Taking it with food or a snack may help reduce the risk of nausea, vomiting, or headaches.

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